June Update

I am currently performing hydrogen/deuterium exchange (h/d exchange) on lysine tetrapeptides of XAAA, which X is lysine or its homolog, and A is alanine. I am also looking into the h/d exchange of b2+ ions of these tetrapeptides. However, there is still a lot of necessary adjustments and testing varying mass spectrometer parameters in order to collect data and increase ion count of b2+ ions in order to perform h/d exchange. I am also experimenting with arginine tetrapeptides where arginine is placed at various positions in the peptide, such as RAAA, ARAA, AARA, and AAAR. Plans for the rest of the month is collecting more data,as well as starting to work up the data (doing calculations) of the rate of h/d exchange.

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