Aug
01

Blast from the Past: A Reflection on the Summer’s Start

Today is my last (official) day of summer research! While I will undoubtedly continue to read and learn throughout the rest of the month, I am taking a moment today to see what I’ve learned and accomplished this summer. I’ve included below my first journal entry from the summer. This entry represents a valuable reflection…
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Jul
30

I’ve Heard It Both Ways: Lessons Learned in Research Challenges

As the summer draws to a close, I have begun to reflect on the overarching challenges and exciting discoveries of my research. While my research is far from over, I have learned several lessons in my extensive review of the literature and vacillating model topics. I’ll summarize my experience at greater length in my final…
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Jul
26

♫ But Now We’re Stressed Out ♫

Happy Friday! I hope everyone is looking forward to a stress-free weekend. As the final week of summer research rapidly approaches, I’ve been burying myself in stress… research! Cell stress may not necessarily match your immediate definition of stress — at the cellular level, protein deprivation, viral infection, and overworked organelles constitute stress, rather than…
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Jul
22

True or fALS? Parallel mechanisms between familial and sporadic ALS-FTD

It’s been a few hectic weeks that have pulled me in several different directions! A quick recap of where we left off — the research literature surrounding the ALS-FTD disease spectrum has compelled me to examine the disease-causing role of membrane-less organelles, specifically those containing RNA-binding proteins (these organelles are generally referred to as RNP granules).…
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Jul
09

In a Bind: RNP Granule Sequestration of RNA-Binding Proteins

Happy July! In cell-ebration of the 4th, I have begun to push my CellDesigner model along, zeroing in ribonucleoprotein (RNP) granules. RNP granules are a class of membrane-less organelles (see last post) that contain RNA-binding proteins (RBPs), RNA, etc., and their dysfunction is implicated in ALS-FTD pathology. RBPs, as previously noted, are prevalent in the…
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