Aug
31

AP axis neural plasticity 4

Hello everyone! Since I took a much needed break in August, this update will be brief and short, yet still full of some interesting results. Before I left, I managed to do a few transplantation experiments. Different from previous ones, which were fixed at stage 18 or 30, this time they were fixed at stage…
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Jul
27

AP axis neural plasticity-3

Hi all! So many exciting stuff has happened in July. The most exciting thing was: I went to Minneapolis! And of course, it was for the Society for Developmental Biology annual meeting. I presented my research at the meeting, got lots of feedback, and attended talks about other developmental biologists’ research for 4 full days.…
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Jun
30

AP axis neural plasticity-2

Hi all! The first week of summer goes by so fast! I’ve had a bunch of exciting progress in my research. First of all, I finished writing the draft of two papers. One of them is about all the findings on AP rotation project before the RNA-seq results. This will become the premise for my…
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Jun
02

AP Axis Neural Plasticity-1

I came back to campus a week early so I could get a head start on my project. Currently, I’ve been trying to clone a list of candidate genes from total Xenopus laevis cDNA that are differentially expressed between sham and rotated transplants (refer to my intro post for more detail. I will then synthesize…
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Apr
10

Molecular Mechanisms of Neural Plasticity Following Anterior-Posterior (AP) Axis Rotation in the Central Nervous System of African Clawed Frog, Xenopus laevis

Abstract: Our preliminary research has discovered that at early (gastrula) stages of development, Xenopus laevis embryos are able to recover from a near complete rotation of their anterior-posterior axis; by late gastrula stages this ability is largely lost. RNA-Seq analysis of RNA extracted from embryos with rotated tissues generated a list of differentially expressed candidate…
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