Aug
28

More Derivatives and More Fluorescence Studies: The Plan for Fall 2015

At the end of summer research, I had synthesized 3-aminofluorenone and two derivatives–one with a flanking methyl group and one with two flanking methyl groups (see this post for structures).  The derivative with the two flanking methyl groups (3-amino-1,8-dimethyllfluorenone) was synthesized successfully but in poor yield, so only 5 mg of product were produced.  While…
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Aug
28

Summer Research Part 3: Presentation at the American Chemical Society National Meeting

After a summer of productive chemistry research, there’s nothing like a relaxing trip to Boston to meet and network with thousands of other chemists from around the world while presenting a poster on the last year’s worth of progress.  So that’s what I did at the American Chemical Society’s 250th national meeting, which was held…
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Aug
28

Summer Research Part 2: Preliminary Fluorescence Studies

After the successful synthesis of 3-aminofluorenone (1) and 6-amino-1,3-dimethylfluorenone (2), we carried out some initial studies on each compound’s fluorescence behavior in a binary solvent mixture of toluene and isopropanol.  Because toluene is a rather non-polar solvent, it does not quench the fluorescence of the aminofluorenones; however, isopropanol contains an alcohol (-OH) functional group–it can thus…
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Aug
26

Summer Research Part 1: Synthesis of 3-Aminofluorenone Derivatives

May
10

Abstract: Effect of Hydrogen-Bonding on the Fluorescence of 3-Aminofluorenone Derivatives

3-Aminofluorenone, an organic molecule with a highly conjugated planar ring system, has a very high quantum yield for fluorescence.  It also shows strong fluorescence quenching (decrease of fluorescence intensity) in the presence of polar protic solvents, especially alcohols (-OH functional group).  This fluorescence quenching is thought to result from solvent hydrogen bond formation to the…
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