Nov
01

October Update

October Update Up to this point, I have performed many synthesis of the precursor aldehyde and have successfully made it. However, the separation of the desired product from the product mixture has been difficult. The particular reaction I followed has a very poor regioselectivity. I went back and looked through literatures on this one specific…
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Oct
01

September Update

September Update Following the synthetic success at the end of the summer, I continued to explore methods that can increase the overall yield of my desired precursor product. I researched different experimental methods that can lead to the same product with better yield. The synthesis was plain and simple; however, the purification was not. I…
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Aug
31

August Update

After countless failures during this summer, something finally seems to work. I have finally synthesized a precursor to my newly proposed ligand design on the very last day of the summer research session. I am optimistic that this is a correct step and will lead to results. The successful synthesis of this precursor will lead…
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Jul
24

July Blog Post–An Alternative Approach

My recent attempts to perform the aromatic substitution have not been particularly successfully. Therefore, I have been looking up alternative procedures to achieve the pendant amine. Initial tests of new procedures on the unsubstituted ligand yielded little amount of product. To work around this, I decided to use the same procedure on the precursor of…
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Jun
30

June Update

During the last month of research, I have found ways to successfully obtain products of the second part of my ligand synthesis. However, I had a lot of trouble trying to purify my crude product to proceed to the next step. Therefore, my next stage of work will be optimizing the ratio of reactants to…
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